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Wound healing is a complex and dynamic process of restoring cellular structures and tissue layers. The study was conducted to compare the effectiveness of cyanoacrylate tissue adhesive with conventional suture in closing laparoscopic abdominal incision. They were randomly assigned to receive either tissue adhesive or suture. Main outcome measures were time taken for skin closure and post operative outcome. Both groups were comparable with respect to age, parity, education level, type of occupation and number of holes. In the study, there was a significant difference in time taken for skin closure where tissue adhesive was much more faster compared to suture. The use of tissue adhesive is easy and safe with complications comparable to suture and results in equally good cosmesis. Therefore tissue adhesive is a suitable alternative to suture in small wounds and low tension areas.
Though the skill & technique of the surgeon are important for wound healing, so is the choice of suture materials. The choice of an appropriate suture for any wound closure will make a large contribution to the final functional & cosmetic result. An histological comparison of sutures is provided here to give readers a full understanding of wound healing when different types of suture materials are used. We sincerely hope that surgeons past, present & future will benefit from this research & thus treat their patients successfully.
Each year, millions of superficial wounds and minor surgical incisions require primary closure by surgeons and primary care practitioners. Sutures are still the most common method of closure of such wounds. However, suturing is time consuming and uncomfortable for the patient. Cyanoacrylate tissue adhesives are the current alternatives for sutures, offering advantages of being painless, less time-consuming and less traumatic to the tissue. This study aimed to evaluate the histopathological aspects of healing in oral incisions closed with silk sutures compared to those closed with Epiglu adhesive. It also aimed to compare time and cost required for each of those two procedure respectively. Results of this study revealed that the use of Epiglu surgical adhesive is convenient for closure of oral incisions, as it can significantly enhance wound epithelialization and decrease the inflammatory phase of healing when compared to conventional silk suture. Besides, the total adhesive cost was almost similar to that of suture, with the bonus of being easier to apply and more time saving. This would definitely have a positive economic impact on both the patient and the health care provider.
Wound is defined simply as the disruption of the cellular and anatomic continuity of a tissue. Wound may be produced by physical, chemical, thermal, microbial or immunological insult to the tissue. Attention should be directed towards discovering an agent, which will accelerate wound healing either when it is progressing normally,when it is suppressed by various agents like corticosteroids,anti neoplastics.or non- steroidal anti-inflammatory agents. Medical treatment of wound includes administration of drugs either locally (topical) or systemically (oral or parenteral) in an attempt to aid wound repair.
Wound healing is essential for survival. The goal of wound management is to close the wound as soon as possible. Improperly managed wounds can be life - threatening, functionally disabling, and cosmetically devastating. Cyanoacrylates (CA) have a variety of medical, dental, and commercial applications as adhesives. These adhesives have been extensively used for closure of cutaneous wounds and in a wide variety of surgical procedures. The increasing use of cyanoacrylates in dentistry, particularly as an adhesive and sealing glue, have raised concerns regarding its potential toxicity in humans. The use of the adhesive reduces treatment time and is a pain-free method of closure, allowing good cosmetic results to the facial injuries.
Wound Closer In Oral And Maxillofacial Surgery Is Art And Science, The Final Out Come After Healing Is Directly Proportional To The Suture Material Used, Skill And Suturing Technique. This Monogram Is Specially Prepared To Give The Young Budding Surgeon And Experienced Oral And Maxillofacial Surgeon To Give Insight Into The Different Modalities In Wound Closer And Material Used For Same. The Chapter On Suture Removal Specialy Written By Author Having 33 Year Of Surgical Practices In Oral And Maxillofacail Surgery.
Wound healing is a natural curative reaction to tissue injury involves the interaction of a complex flow of cellular events that generates resurfacing, reconstitution, and restoration of the tensile strength of injured tissue. Diabetic patients are suffering from delayed wound healing due to abnormality in the progression of normal wound healing phases. Lymphocytes are playing central role in wound healing and its augmented apoptosis due to hyperglycemia leads to delayed wound healing. Prolonged delayed wound healing revolves into chronic wounds which finally ended by amputation. We showed that oxidative stress is playing one of the major role in attenuation of lymphocyte apoptosis in diabetic patients. Better understanding of factors involved in lymphocyte apoptosis may be important to open new traditions for the management of wound healing.
This book represent a new challenge in the Laser therapy field. It takes the effect of diode laser on the healing of wound from a molecular level by using immunohistochemical staining technique which represent one of the most advanced method used in histology and pathology. Low Level Laser effect on the biological tissue still need for further studies and by using immunohistochemistry the answers of many questions could be found.
Currently staples are widely used in orthopedics, scalp & abdominal surgeries and are also very helpful in securing grafts with or without the help of sutures. Advantages of staples include rapid placement, excellent cosmetic results, less tissue strangulation than sutures, minimal tissue reactivity, and low incidence of wound infections. Reported disadvantages of staples include interference with computed tomography scans, less meticulous approximation of wound edges and cost. Skin staples are better alternative to conventional sutures in head & neck cancer surgery as they offer: Ten times faster wound closure than sutures. Cost effectiveness if total cost of closure is considered although cost of material was almost double than suture closure. Similar results to sutures in terms of patient comfort, aesthetics outcome and complication rate. The book is useful both for the graduates and the postgraduate students of general surgery and dentistry.